ABSTRACT
Chronic rhinosinusitis is a common disease and frequently encountered disease in otolaryngology, but the therapeutic effect is not ideal. While its pathogenesis is exploring in the continuously. Found in the recent years, Th17 cells are a new subset of T cells and closely related with inflammatory disorders, autoimmune diseases and cancer. Its differentiation, regulation and biological effects are widely noted as a hot area of research. This review explores the discovery of differentiation and regulation of Th17 cells, the relationship between related cytokines and chronic rhinosinusitis, in order to have a beteer knowledge of chronic rhinosinusitis. This review regards Th17 cells as the main clue, nevertheless, lacking consideration of the impacts of other factors on chronic rhinosinusitis.
Subject(s)
Humans , Chronic Disease , Rhinitis , Allergy and Immunology , Sinusitis , Allergy and Immunology , Th17 Cells , Allergy and ImmunologyABSTRACT
This paper discussed the main point specifically from the three aspects which are the certainty and uncertainty of technological function , the predictability and unpredictability of technological efficiency , and“should do”or“not should do”of technological application .It presented an ethics argument of medical technology clinical admittance restriction and defends the standpoint -what we can do does not mean what we should do , aiming to provide moral theoretical support of ethical review of medical technology application .
ABSTRACT
Objective To evaluate the effect of clinical pathway in pulmonary thrombus embolism (PTE) .Methods 60 cases of PTE were admitted department of respiratory from 2011 to 2012 and divided into the experimental group and the control group ,30 cases for each group .The control group was implemented with normal process of hospital management while experimental group de-veloped clinical pathways .The efficacy ,department of respiratory drug costs ,complications and patient satisfaction were recorded and computed .Results The average department of respiratory and drug costs in experimental group respectively was (17 .13 ± 2 .22)days ,(16 545 .04 ± 1 557 .44) RMB and (7 050 .83 ± 372 .74) RMB ;less than (19 .77 ± 3 .41)day ,(17 709 .45 ± 1 902 .05) RMB and (7 345 .75 ± 450 .82) RMB in control group ,there were significant difference between the two groups (P0 .05) .Conclusion The effect of clinical pathway in PTE have a positive role in reducing hospitalization time ,total costs ,drug costs and increasing satisfaction ,it is worth to develop in primary hos-pital .
ABSTRACT
OBJECTIVE@#To investigate the clinical efficacy of revision surgery of nasal septum with reformed incision under nasal endoscope.@*METHOD@#Thirty-seven patients with failed septoplasty were carried out revision surgery of nasal septum with reformed incision.@*RESULT@#Revision surgery of nasal septum with reformed incision was successful in all cases. The symptoms resulting from the nasal septal deviation disappeared or significantly relieved. Following successful revision surgery, the treatment outcomes of concomitant nasal and/or sinusal diseases also significantly improved.@*CONCLUSION@#The adhesive fibrous tissue in septal mucosa were successively separated in patients with revision surgery of nasal septum with reformed incision under nasal endoscope. Revision surgery of nasal septum with reformed incision was easily and safely, and with fewer complications.
Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Endoscopy , Nasal Septum , General Surgery , Nasal Surgical Procedures , Methods , Rhinoplasty , Methods , Treatment OutcomeABSTRACT
OBJECTIVE@#To investigate the effects of intranasal steroid on nasal mucosa in rat model of allergic rhinitis (AR).@*METHOD@#Thirty-six SD rats were randomly divided into three groups (each included 12 rats): the intranasal steroid group(group A),the allergic rhinitis group(group B) and the normal control group(group C). AR model was reproduced by ovalbumin in group A and B. The control group was allergized by NS instead of ovalbumin. Group A was used steroid spray in nasal and Group B and C was used normal saline. Then ,after the last provocation,the allergic symptoms were evaluated,the number of eosinophil (EOS) of the rats' nasal mucosa was counted under hematoxylineosin staining and the goblet cells was counted under alcian blue-periodic acid-Schiff staining. The morphological changes of the rats' nasal mucosa were observed by scanning electron microscope.@*RESULT@#Compared with group B,the inhibition of nasal symptoms was found after used of steroid spray in group A. The EOS and the goblet cells in group A was significantly different with that in Group B (P 0.05). Observed by scanning electron microscope, the cilia of the epithelium in group B were significantly lodging, disoriented, winding and secreting,while the cilia of the epithelium in Group A and C had similar appearance.@*CONCLUSION@#Intranasal steroid spray can relieve symptoms and inflammatory conditions of nasal mucosa in allergic rhinitis, and can repair injured nasal mucosa cilia.
Subject(s)
Animals , Rats , Androstadienes , Pharmacology , Anti-Inflammatory Agents , Pharmacology , Cilia , Disease Models, Animal , Inflammation , Nasal Mucosa , Pathology , Rats, Sprague-Dawley , Rhinitis, Allergic, Perennial , Drug Therapy , PathologyABSTRACT
"Be cautious alone"is a important idea of Confucianists,it means that one should be very cautious to obey every moral standard and not to do any immoral things when he is being alone.The character of purchasing and the particularity of Medical substances demand that Medical substances buyers must be cautious when being alone."Be cautious alone"may help buyers to increase their self-discipline and arouse their vigilance to check erroneous ideas at the outset,and help them to culture a harmonious purchaseing idea.